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India Probes 4 Cough Syrups After WHO Alert On 66 Child Deaths In Gambia

News Insider's Desk by News Insider's Desk
October 6, 2022
in National
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New Delhi: The government has started an investigation into four cough syrups manufactured by a Haryana-based pharmaceutical firm after the World Health Organization (WHO) warned that they could be linked to the deaths of 66 children in The Gambia.

Top sources in the Ministry of Health and Family Welfare said the WHO alerted Drugs Controller General of India (DCGI) about the cough syrups on September 29. The Central Drugs Standard Control Organisation immediately took up the matter with the Haryana regulatory authority and launched a detailed investigation, the sources said.

 

The cough syrups have been manufactured by M/s Maiden Pharmaceutical Limited in Haryana’s Sonepat, the sources said. They added that as per the information available at this point, it seems the firm had exported these products only to The Gambia. The company is yet to respond to the allegations. The firm’s administrative office in Delhi’s Pitampura was found shut this morning.

 

The WHO has warned that the syrups may have been distributed outside the West African country and a global exposure is “possible”.

 

WHO chief Tedros Adhanom Ghebreyesus told reporters yesterday that the four cold and cough syrups “have been potentially linked with acute kidney injuries and 66 deaths among children”.

 

Sources from the ministry said the “exact one to one causal relation of death” has not yet been provided by WHO”. They added that the WHO is yet to share the details and photos of labels confirming the manufacturer of the products.

 

The WHO has not yet provided details on when these deaths took place.

 

Samples of the four cough syrups, sources said, will now be tested in central and regional laboratories and results will come in within two days. The sources said that as per protocol, any drug exported from India is tested by the recipient country. The question is why was the contamination not detected during testing in The Gambia, the sources said. They also said that the WHO has not informed whether the drugs were used in the west African country without testing.

 

According to the WHO alert, the four products are Promethazine Oral Solution, Kofexmalin Baby Cough Syrup, Makoff Baby Cough Syrup and Magrip N Cold Syrup.

 

“To date, the stated manufacturer has not provided guarantees to WHO on the safety and quality of these products,” the alert said, adding that laboratory analysis of samples of the products “confirms that they contain unacceptable amounts of diethylene glycol and ethylene glycol as contaminants.”

 

Those substances are toxic to humans and can be fatal, it said, adding that the toxic effect “can include abdominal pain, vomiting, diarrhoea, inability to pass urine, headache, altered mental state and acute kidney injury which may lead to death.”

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